Warfarin and side effects

Hi everyone. I have to take 3 mg of Warfarin and 7.5 mg of Lisinopril daily because I have had a heart valve replacement together with a triple bypass. I have been taking the Warfarin for over two years now, and the Lisinopril for about five years. The problem I have had since taking the Warfarin is that every eight to ten weeks, I have a six-hour vomiting period that happens about three hours after any meal I have had. I only vomit up fluids with the odd small piece of solids that is no more than the size of a current. Obviously, it is not very nice for the six hours I am vomiting, on and off every 20 to 30 minutes or so. My doctor does not know for definite what is causing it. My meal regime hasn’t changed so it can’t be food related and I don’t drink alcohol either. I am on a waiting list to have a camera put down my throat and into my stomach to see if there is something going on in there that I/we don’t know about.
I have posted this on the off chance that someone else has been in the same position as me and if they could throw some light onto what is causing the vomiting every eight weeks or so.

Aarrgghh. You have my very deepest sympathies.

I see the results of long term warfarin damage in Hon No.1 Daughter.

Over a couple of decades it effectively destroyed her immune system, thyroid function and digestion. Eventually it took several years exhausting effort to persuade her consultant to put her onto alternatives that self regulated anti-clotting and thyroid instead of needing frequent blood tests. I don’t know the full story! She still takes a vast assortment of other meds for other conditions consequential on the warfarin damage.

I’m not a medical person, and I cannot tell you what the medications are, but she is proof alternatives do exist. Talk to your doctor/consultant and also research them yourself for your specific conditions as well. Warfarin is the cheapest oral med to prevent clotting, which is why it is usually top of the NICE list, but it might not be the most relevant.

Keep on asking them about it, and good luck!

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About 12 years ago I was about to be put on Warfrin but at last minute it was decided on the alternstive Riaroxaban which has given me no problem so far

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Been on Lixiana Endexoban thinners (with 6 other pills every AM for 14 months for Critical Heart Failure .
Imagine a 4 pot engine with 3 plugs pulled, and the last one is arcing a bit.
It’s improved to just “Chronic”.
This is good. I’ve developed a habit of still waking up AM breathing.
I’m battling on merrily on nearly 2 pots now.
Point is, that’s just me…no bad side effects from anything bar a bit tired now and then.
Mind you Pollyanna, we’ve past our 3 score and 10 so every day is a bit of a gift!
I would say stick with your clinicians and try to stick it out.
They will find out.
None of us are qualified as far as I know…so…
All the best.

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I was put on anticoagulants after being diagnosed with pulmonary embolisms 3 years ago, (I was very lucky that they spotted them in time) I’ve been on 10mg Riaroxaban daily ever since with no further problems and the embolisms have shrunk away.
It’s definitely worth asking your Dr if Riaroxaban is appropriate for your condition.

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The consensus appears to be that there are alternatives.

I had to self inject with anticoagulants last year and when I asked about Warfarin they said “oh, they don’t use Warfarin any more”.

It is a natural product produced by mouldy, red clover. Not a lot of people know that.

If the Warafarin is the issue, or liklely to be, the obvious question is whether there is an available, suitable substitute.

Perhaps your doctor thinks there is good reason to put you through this but I’d certainly raise it.

Newer drugs exist, I don’t know all the pros and cons but I know they are less of an issue for monitoring/management.

Thank you everyone who took the time to reply to my post. Unfortunately for me I should not, according to the NHS Drug site take any of the drugs that have an at the end of their description, like Apixaban as I have had a heart valve replacement yet, my doctor prescribed all four types of medication like Apixaban for me over a period of twelve months. When I told the doctor that I should not take any of these, according to the NHS Drug website the doctor looked shocked.

You can also talk to your local Pharmacist, they quite often know of alternatives that your Doctor may not have considered - naturally you then have to discuss their recommendations with the Doctor so they can decide/prescribe it.

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Apixoban ARGH !!! given to me as my High Blood Pressure treatment tablets were old hat according to the hospital specialist not my GP - result ? - two or three days later I had a bleed on my brain and a mini stroke . That was in 2014. fortunately I survived to drive my MX5 !

Hi everyone, since my first post I have had an Endoscopy at the hospital, which wasn’t all that disturbing, and the doctor told me as soon as it was completed that everything in my stomach was fine. Although he had taken a few biopsies he said as he had not found anything untoward, they wouldn’t be checking the biopsies for about three months. Six days later I made an appointment to see a practitioner at my regular surgery, who is supposed to be very knowledgeable about drugs.
I told her about the problems I have every two months and she couldn’t suggest an alternative. Later when at home and clutching at straws, I remember that I had been using saccharine sweeteners in my twice daily cups of coffee from about the time I went onto warfarin, so just in case, I have stopped taking them and now I drink my coffee without any sweeteners. I have about five or six weeks to wait now to see what happens at about eight weeks from vomiting last time.
The strange thing is that for an eighty-seven-year-old guy I am fine the rest of the time apart from a few normal aches and pains that you would expect in an old body like mine.
Just as an aside, I have lived, up to now, in ten decades. I hadn’t thought of this until my neighbour across the road from me mentioned it. His mum is the same age as me.

That reminds me of the story of the little boy who’s teacher asked “If Shakespeare was alive today, what would he be famous for?”
His hand shot up immediately.
“His age Miss!”

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